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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35de66dde8484d168c62d452d97b8c67a33d8725dc431c98d61fc46bae9329d7' 
  AND token = 'UHv4BM72FYWhEhBdbY35N1Tqx+h+It/Ymo3aaqkTrw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}