SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef79f100c149a6e9336cba17350f9fdf8c199fa91f938a48a066df5af9fc94f' 
  AND token = 'UGISSStFTHRk/kyGZB5AISIQyt6mT8XvroVUoMCsEa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}