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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c68a33fc095ae5a5998635d0f38df8423c5ae04d3c345036c6a084314ada918' 
  AND token = 'ss8wdOVzfr0ki+dvZMQc8cv3tSHcx0KuRA1WVY/uvc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}