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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e7d7927d6fb2402e8b7bdadc68a94c38f30576b4752bd70204613e6ebec994' 
  AND token = 'ffVeFuiLp8ZlXOGjMCjxVbLW3CvL/Y52A20paoR19xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}