SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f47cdf7f66a67d04020532b9abe2e189b285f55ddefee715212be0d88011a7' 
  AND token = 'GxQgAeOSHS5Fl6xQJhidG/UCDKlRyBOJsQf31LFBhmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}