SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad853df82e10ef42fabb8bc3596ffc4571ebf56e20af0cf5a003327b0ce5296a' 
  AND token = 'x5Kp5IWr7GC7ZasuSzyLwlC5Mhs+pz3gQqDpRrsyuPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}