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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8a81106001b548ddeb0ba1abc1d002ed0b35898b52e71305c427eff2cc471a' 
  AND token = 'fxQ9aMNnZgbtI48AzWl5VVDN8FM863I/Ztol16Ph868=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}