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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d2a182244fb0a63d441adf4307da9f297f5050a2039ca47d636d1c6a64bfde8' 
  AND token = '7xze8LEyIo3Oo6KZabTNo+qToBUntCU3tzDZYuA+dKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}