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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e76ee860bde53236ec8984d93a18a52a731007b3cf5f98d8179847b1ff133c6' 
  AND token = 'MmW75+8PSkL9M3x70/penl5dNpV5bHQLGLIKK3Je4gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}