SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e06353f09ec6d398d8d96af57f7f3ed887192be1f64aed3554d5ecb1fd0155' 
  AND token = 'Wd89uqmmtIHwolSBB0/2Shy6KVHwdhQ8aQV0W+U1mbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}