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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c95899a646987dfa8c52ced845c41474b0ff6c240bcf7208ca5df6a20a4601' 
  AND token = '+kYDHEFGTZprIsDlJxaZ8/2ihmNGLEz6u/nNmUy1IA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}