SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0462adb41feab3cd85a847b1fb9aeccb6cdb9a8348b0a1debee23de6ec618a' 
  AND token = 'qVDBDrWBinK059JHj6GJmnlFDqaAp2RJRKv7RKEoxyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00126

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}