SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8e08f3c8cfb6ab339afe9281bdad8f5580d4aa607ab1708984424f87111074' 
  AND token = 'UREUsDMltqA1J8mASaNCNOVNSf0QKbZCCi5/PeRl8S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}