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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e728323f6e37fb397b5050e71ca170ac62f75f06eb214b5c3f4856f123b652c1' 
  AND token = 'tsie1MiI9kHvmTh1+tV8eMZjslIVYZ4CgNWrmcgD1G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}