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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0468c5116f1abcaae88afd526b3bb2729662fc9cb2c109a7abbdef7fe4c565a7' 
  AND token = 'LMM/X5nX94Hfe9KzR7UggpqNbQXLYYwHieIQud9NSRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}