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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db59de00e6e32b0db8b0419507c82818798835b7eb8521ab2854896dc967951b' 
  AND token = 'p0Yw8av9rw0coJJApETwvBpDTGhFciNBOWXuRMY56mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}