SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222eb278966a703ef5162506eb00e9dbeb4d7d7486c1e6ff4087af6fa7863f4d' 
  AND token = 'GGQ2p0kiam2P0NB41/YYELtsvCAlHhmaLsaNRnS5w5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}