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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f36792c287d6c13017fd011f85bb47854f873426f64a3366c6f2c21b3f54e61' 
  AND token = 'lv5KcIZFxwdSUGcLY4FGNmfXW4aK7v1g7FWGJxY0Qlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}