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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6274422d0f47dccd4b1b9c65241feb4f61410736e162df21eb259be35521ea31' 
  AND token = 'XCQxr3zJ/I2XnyPiyvH5ei4uh0l3MdhX2TdqaLyc3u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}