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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c35e3afee54efae0ba238dafb6fbebca27910c9c16087cb3e4823e25b9dc2e1' 
  AND token = 'KbNyr1CL1cQkQK/NbActnrGUhQkiFK5uwwwF+0/uIB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}