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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9c41d2aa80920f3f467c003e2c77a55c629be8021bd1922767cd068c0f3e63' 
  AND token = 'udsvEt+8NVhXh7okns+KRKfP11E7OY8/4zpFPr15Sf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}