SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb88fd8eaf8ecdbc263f305185690c20b8133eea909da2d4b1a4eeb90eabbd09' 
  AND token = 'Kjy7HxDHq5KO3LoPVMMey32qdAAOqFKHydDnNgXM/r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}