SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008a78f08e936d5f828b0be71c2f67f17ef0bbdfd5e1649f910dabac4466f630' 
  AND token = 'SISJ76swroGE/ULBLBGNMdTiO0yeS9QAvvUVzUxwwyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}