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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce9d0395ba9eab43c1b614c42f6a3b3e7c784058b679305e1691ab446d6dec44' 
  AND token = 'w2hCtQD4qNVvzWRh1VEvA2WDfGzyCd6XEaflRBQ2Ji0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}