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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408b04e62f8eaa2362e96e58024b224121a1c4dda583b0e46e035db8ee9a3883' 
  AND token = 'L5hlBkzr25AQ0g4K0ctOiW2fLBnFc/GuhD1bUnyRr4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}