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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5add429648ac0887d68a7c0a9ac42e22e60d656ef5c15280b0438a6800a7479' 
  AND token = 'W001wSEXW72B7mifArLqIrC7oW7W5IAqH/ItBDh0E1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}