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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45305882e63bd208f36426a4096f6d6f2dc829084efb9572a64928216c8b3b87' 
  AND token = 'Apij4jL9nSdLU+x6CtYemAOVzv4sFLPL9ArK2symkRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}