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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b729c7c49f544b3acd842b86ac0a0ee8409ed9a3b0bb21b9ec8c26e1440e8f0' 
  AND token = 't43EdryXUblpOGTcp0jOU9tS7cjstcJOsbJk6rE1d70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}