SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f9d09d208b869cf7617159683a688b1f5dcd6cbf97b9ce5165ce63cc3ccbbfe' 
  AND token = 'RXo4TD248KSWrDBa4v4tIN79dkd5sALrZ6VskAT8kOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}