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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f4d1d1063eeed68c50aa6bc53ee46093c351008aada211406fc6eddfa7ac57' 
  AND token = 'wcWbI0afDFF50JsOY5FxCKEDNpzDH2hKAy2+sZx4CJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}