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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd85d49db8bb432b7b5d9512c0f6e95fa2fbc354d6b1d685afdf1e13033971ca1' 
  AND token = '33d6ECH8c5DcZsMRTxNS6i4/rebxgdldi4kwzdev0Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}