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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2bc22c9912953012b9696d9805e19cbff638e32cd0768ed04141b06fc7a606f' 
  AND token = 'f63Mdnl7bgC9wlegA1qkwil7NFth0jG8VW6bd5+KDeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}