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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b12f6888d0f8e7421fce7bfb4ea57a664d16aa4c3e658c4d6ba81921b217fa8' 
  AND token = 'PiBQiNB+5VhZHWovWulo+YYbsDDyx/n4VWW82vDJMH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}