SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94b550f92c5279781f2091fa490da7fa6fbca90ed9e67697978abc74931d55c5' 
  AND token = 'LYMDOmDPB+MkKr4TH81GpR6WreKRqVmuRCTJ0dLcxIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}