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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e2d2ead9d2d92afa28fe41ccee6ab3e141bb54cd0e0292225c0c5117660f64' 
  AND token = 'VcxfyOu7La0de1AhV2SmGtQMXPUd6U080CbWLObauEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}