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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bca2f1a0c18f2c5269f1aaba406bb6b8fcfe1b3099d4f237d5816186d7e5433' 
  AND token = 'br8GU+7i2A9xyy4wnwy1F1cYKqORdOGFPuusHkLeaBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}