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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68367dcd47b1e302608014b2248584fc186a34e49720012828726ba632c71f5c' 
  AND token = 'N8UmiPsGRn7VitsBwnz5WO9P6n9IdKgz51E9qFWWRM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}