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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522eed256e09d9b099fb759581b071cbf2a803789a47f1e7980b7466ada99f0a' 
  AND token = 'Vz87EnvWdKDS3AUwbrt+qP2IbFRWOA+DJA2zzk0RUS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}