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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fc80021e1d391841df7fe8fec7cae39f4b0048aaccb10f672835c7c819eb54c' 
  AND token = 'Iq/bmf1FAd5sbg0KbnZXA9V8EGHA/UhwqTb3zj4gCO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}