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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3a2b94d3099d85cecb70e92516fae0454751cb585058d0ab1efa8012860d23' 
  AND token = 'ZCmoj+hDbl3bkesBNiUkEuG6oUNr0HhGjRIG1b4WyR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}