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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6644430df625c26123207fb63be2c793eb223c59a065105cf0415e1d7234829c' 
  AND token = 'znMa5jKoo2RqUJmDRbGxlSFEQpgWaWeOGfR7HI7r0dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}