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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '007b7c72c634c99b51c0a39822cc133ecbc0a4e287926254b054cc7c42a6999f' 
  AND token = 'PSmOwTqj0SDsAvR+hdrKT6oW65qosWkMLr+rImqOtPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}