SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93be7be937eb9d84bb82ec89628cf90598fe4657e76b3849c2122c3a74df3d02' 
  AND token = 'Avx7hYrE25DTfd3o8zpiyyB2v3Ekx0/dzZWoRkzpZXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}