SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8126e03a0967b3a234be151f8ec815948325ab3c9db9d6659e836c750c8890a3' 
  AND token = '0KSsOBm8HPB1g912zXjj19tTVTzUw98mEFocuTeka00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}