SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8f254113ff60573ce522f8d08c516eaa62e1491a4030145aa342613f01aff4' 
  AND token = 'lZOtaMBDMcKggfe2CE7DDA66W6KYBORpbAdXjTCM/ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}