SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3a4225a7e20916eeb3caed8649876f11fdc8be2c1ec57584b6a14ac9891df1c' 
  AND token = '8uTyrERc5pH+UQPa24q7UEHJ28KKp/j3PrHALK52BCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}