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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499e866d7537754a4893f242b35964abba1d93178fcce25c5a8cf570043913b1' 
  AND token = 'cxRNgrgSPRe2iRBSQVsaj/wQk35uWLnMQrZqkbUuaSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}