SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4edb36a0b20a113145bdd138c13e99cf4d73421b7066c46a308af828d31645b8' 
  AND token = 'ezOt1A4P+JuXW51zLOQLhLOXpsd6LVQgLAZuumiXWHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00242

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}