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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888570e69d639f508b9b10366669b148e359120f46c749874e13443d094cdddd' 
  AND token = 'mVOZ/U8As8gSM/R+thpMWll//hseiGeo49Kz5PlOo6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}