SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6000feececa9ca4f4b2f4187e7a6f2389999705d3dffa5be8e853232aa409078' 
  AND token = 'iYi4N9cf9Oh673aWC/0tfi8NKYOPs27bCaipOA45UG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}